Yep, that’s leptin resistance for you. Obesity is really a hormonal condition, and this is why GLP-1 inhibitors are so effective - they actually treat the hormonal condition and allow the recipient to manage their food intake without having their body hormonally work against them.
A layman’s explanation (to be clear, I am the layman) of my best understanding of the subject:
Hunger is controlled by 2 hormones:
Ghrelin, which causes hunger and is produced by the stomach
Leptin, which suppresses hunger and is produced by fat cells
As fat cells accumulate, leptin levels also increase, but a person that has developed leptin resistance will not feel the appropriate amount of hunger suppression from the leptin, leading to chronic hunger unless large energy intake is sustained.
I’ve been on a glp1 medication to treat obesity for about 2 months now, and its wild how well it works. Im down about 25 lbs. The most striking part to me is that I took a week off during month 2 because I needed a break from feeling sick and fatigued all the time, and during my break week I was getting full on just under half the food I’d eat in a sitting prior to starting the medication.
All that being said, im still convinced that the most effective part of ozempic is how fucking sick it makes you feel all the time. In my case its gotten to the point that the threat of digestive pain caused by eating while on ozempic is a bigger motivator than hunger; 5 days a week lately my food intake is “enough greens to make fibrous poop, enough crackers to absorb some of the excess stomach acid and mitigate heartburn, and a multivitamin”
Im right there with you, but with beer. I used to have a beer or 2 every night after everyone was in bed. Sit down in the basement and load up a game or show. Decided to stop doing that, and had no urge to drink through out the day, but as soon as id go downstairs and fire up the games, id reach for beer that wasnt there. It was purely habit at that point for me.
As others do to curb their snacking habits, i just dont buy it, because that urge doesnt exist during the day
My “food noise” in my brain slows down a lot when I reduce my carb intake. I tend to eat fewer calories when I’m not eating as many carbs from processed foods (including bread, pasta, white rice). If I limit my carb sources to higher fiber, higher protein foods, I tend to naturally eat significantly less, and can go a lot longer before feeling hungry.
I’m not sure how the insulin, leptin, ghrelin, and blood sugar levels play into all of it, but I know that I generally stop thinking about food as much when I’m not eating too many processed carbs.
Does either of those cause/prevent actual starvation feelings, like headaches and fatigue? Do they influence your non-exercise activity thermogenesis? (ie, feeling like you need to sit while you wait for the bus instead of standing or pacing) Or is it just a vague munchiness?
Does either of those cause/prevent actual starvation feelings, like headaches and fatigue?
yeah, mostly
if there’s no readily available food i can go a full day without feeling anything, and i only eat again only because of munchiness, not because of hunger. There’s the occasional stomach rumble after 12hrs of not eating but nothing significant enough to tell the brain “you should try to not die”
Yep, that’s leptin resistance for you. Obesity is really a hormonal condition, and this is why GLP-1 inhibitors are so effective - they actually treat the hormonal condition and allow the recipient to manage their food intake without having their body hormonally work against them.
A layman’s explanation (to be clear, I am the layman) of my best understanding of the subject:
Hunger is controlled by 2 hormones:
As fat cells accumulate, leptin levels also increase, but a person that has developed leptin resistance will not feel the appropriate amount of hunger suppression from the leptin, leading to chronic hunger unless large energy intake is sustained.
I’ve been on a glp1 medication to treat obesity for about 2 months now, and its wild how well it works. Im down about 25 lbs. The most striking part to me is that I took a week off during month 2 because I needed a break from feeling sick and fatigued all the time, and during my break week I was getting full on just under half the food I’d eat in a sitting prior to starting the medication.
All that being said, im still convinced that the most effective part of ozempic is how fucking sick it makes you feel all the time. In my case its gotten to the point that the threat of digestive pain caused by eating while on ozempic is a bigger motivator than hunger; 5 days a week lately my food intake is “enough greens to make fibrous poop, enough crackers to absorb some of the excess stomach acid and mitigate heartburn, and a multivitamin”
The annoying thing for me is, that I feel the urge to eat something, even though I don’t feel hungry
I feel it’s a trained habit from eating snacks and dinner while watching stuff in the evening
It’s a “I’m not hungry, but having a tasty dinner or snacks to watch this show would be great” urge
It’s super annoying, because ADHD meds already take care of most of my hunger feeling, but getting rid of that conditioning feels a lot harder
The Japanese have a word for it: kuchisabishii 口寂しい - lonely mouth.
Sounds like smooching or oral sex would take care of the urge …
That’s a great word for it
Im right there with you, but with beer. I used to have a beer or 2 every night after everyone was in bed. Sit down in the basement and load up a game or show. Decided to stop doing that, and had no urge to drink through out the day, but as soon as id go downstairs and fire up the games, id reach for beer that wasnt there. It was purely habit at that point for me.
As others do to curb their snacking habits, i just dont buy it, because that urge doesnt exist during the day
My “food noise” in my brain slows down a lot when I reduce my carb intake. I tend to eat fewer calories when I’m not eating as many carbs from processed foods (including bread, pasta, white rice). If I limit my carb sources to higher fiber, higher protein foods, I tend to naturally eat significantly less, and can go a lot longer before feeling hungry.
I’m not sure how the insulin, leptin, ghrelin, and blood sugar levels play into all of it, but I know that I generally stop thinking about food as much when I’m not eating too many processed carbs.
I learn so many great things from reading the comments in Lemmy greentext posts.
Does either of those cause/prevent actual starvation feelings, like headaches and fatigue? Do they influence your non-exercise activity thermogenesis? (ie, feeling like you need to sit while you wait for the bus instead of standing or pacing) Or is it just a vague munchiness?
I don’t know the subject well enough to tell, unfortunately.
yeah, mostly
if there’s no readily available food i can go a full day without feeling anything, and i only eat again only because of munchiness, not because of hunger. There’s the occasional stomach rumble after 12hrs of not eating but nothing significant enough to tell the brain “you should try to not die”